European University Institute Library

Stochastic Dynamics in Computational Biology, by Stefanie Winkelmann, Christof Schütte

eng

0

non fiction

Stochastic Dynamics in Computational Biology

electronic resource

dictionaries

1229075475

by Stefanie Winkelmann, Christof Schütte

Frontiers in Applied Dynamical Systems: Reviews and Tutorials,, 2364-4532Springer eBooks.

The aim of this book is to provide a well-structured and coherent overview of existing mathematical modeling approaches for biochemical reaction systems, investigating relations between both the conventional models and several types of deterministic-stochastic hybrid model recombinations. Another main objective is to illustrate and compare diverse numerical simulation schemes and their computational effort. Unlike related works, this book presents a broad scope in its applications, from offering a detailed introduction to hybrid approaches for the case of multiple population scales to discussing the setting of time-scale separation resulting from widely varying firing rates of reaction channels. Additionally, it also addresses modeling approaches for non well-mixed reaction-diffusion dynamics, including deterministic and stochastic PDEs and spatiotemporal master equations. Finally, by translating and incorporating complex theory to a level accessible to non-mathematicians, this book effectively bridges the gap between mathematical research in computational biology and its practical use in biological, biochemical, and biomedical systems.--, Provided by publisher

Introduction -- Well-mixed stochastic reaction kinetics -- Population scaling -- Temporal scaling -- Spatial scaling -- Summary and Outlook -- Mathematical background