Coverart for item
The Resource Simple Mathematical Models of Gene Regulatory Dynamics, by Michael C. Mackey, Moisés Santillán, Marta Tyran-Kamińska, Eduardo S. Zeron, (electronic resource)

Simple Mathematical Models of Gene Regulatory Dynamics, by Michael C. Mackey, Moisés Santillán, Marta Tyran-Kamińska, Eduardo S. Zeron, (electronic resource)

Label
Simple Mathematical Models of Gene Regulatory Dynamics
Title
Simple Mathematical Models of Gene Regulatory Dynamics
Statement of responsibility
by Michael C. Mackey, Moisés Santillán, Marta Tyran-Kamińska, Eduardo S. Zeron
Creator
Contributor
Author
Subject
Language
eng
Summary
This is a short and self-contained introduction to the field of mathematical modeling of gene-networks in bacteria. As an entry point to the field, we focus on the analysis of simple gene-network dynamics. The notes commence with an introduction to the deterministic modeling of gene-networks, with extensive reference to applicable results coming from dynamical systems theory. The second part of the notes treats extensively several approaches to the study of gene-network dynamics in the presence of noise—either arising from low numbers of molecules involved, or due to noise external to the regulatory process. The third and final part of the notes gives a detailed treatment of three well studied and concrete examples of gene-network dynamics by considering the lactose operon, the tryptophan operon, and the lysis-lysogeny switch. The notes contain an index for easy location of particular topics as well as an extensive bibliography of the current literature. The target audience of these notes are mainly graduates students and young researchers with a solid mathematical background (calculus, ordinary differential equations, and probability theory at a minimum), as well as with basic notions of biochemistry, cell biology, and molecular biology. They are meant to serve as a readable and brief entry point into a field that is currently highly active, and will allow the reader to grasp the current state of research and so prepare them for defining and tackling new research problems.--
Member of
Assigning source
Provided by publisher
http://library.link/vocab/creatorName
Mackey, Michael C
Image bit depth
0
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
  • Santillán, Moisés.
  • Tyran-Kamińska, Marta.
  • Zeron, Eduardo S.
Series statement
  • Springer eBooks
  • Lecture Notes on Mathematical Modelling in the Life Sciences,
http://library.link/vocab/subjectName
  • Medicine
  • Gene expression
  • Systems biology
  • Differential equations
  • Applied mathematics
  • Engineering mathematics
  • Probabilities
  • Biomathematics
Label
Simple Mathematical Models of Gene Regulatory Dynamics, by Michael C. Mackey, Moisés Santillán, Marta Tyran-Kamińska, Eduardo S. Zeron, (electronic resource)
Link
http://ezproxy.eui.eu/login?url=http://dx.doi.org/10.1007/978-3-319-45318-7
Instantiates
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- Part I Deterministic Modeling Techniques -- 1.Generic deterministic models of prokaryotic gene regulation -- 2.General dynamic considerations -- Part II Dealing with Noise -- 3.Master equation modeling approaches -- 4.Noise effects in gene regulation: Intrinsic versus extrinsic -- Part III Specific Examples -- 5.The lactose operon -- 6.The tryptophan operon -- 7.The Lysis-Lysogeny Switch -- Index -- References
Control code
978-3-319-45318-7
Dimensions
unknown
Extent
1 online resource (XIV, 124 pages)
File format
multiple file formats
Form of item
  • online
  • electronic
Governing access note
Use of this electronic resource may be governed by a license agreement which restricts use to the European University Institute community. Each user is responsible for limiting use to individual, non-commercial purposes, without systematically downloading, distributing, or retaining substantial portions of information, provided that all copyright and other proprietary notices contained on the materials are retained. The use of software, including scripts, agents, or robots, is generally prohibited and may result in the loss of access to these resources for the entire European University Institute community
Isbn
9783319453187
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-3-319-45318-7
Other physical details
20 illustrations in color.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(OCoLC)962750882
Label
Simple Mathematical Models of Gene Regulatory Dynamics, by Michael C. Mackey, Moisés Santillán, Marta Tyran-Kamińska, Eduardo S. Zeron, (electronic resource)
Link
http://ezproxy.eui.eu/login?url=http://dx.doi.org/10.1007/978-3-319-45318-7
Publication
Antecedent source
mixed
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
not applicable
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- Part I Deterministic Modeling Techniques -- 1.Generic deterministic models of prokaryotic gene regulation -- 2.General dynamic considerations -- Part II Dealing with Noise -- 3.Master equation modeling approaches -- 4.Noise effects in gene regulation: Intrinsic versus extrinsic -- Part III Specific Examples -- 5.The lactose operon -- 6.The tryptophan operon -- 7.The Lysis-Lysogeny Switch -- Index -- References
Control code
978-3-319-45318-7
Dimensions
unknown
Extent
1 online resource (XIV, 124 pages)
File format
multiple file formats
Form of item
  • online
  • electronic
Governing access note
Use of this electronic resource may be governed by a license agreement which restricts use to the European University Institute community. Each user is responsible for limiting use to individual, non-commercial purposes, without systematically downloading, distributing, or retaining substantial portions of information, provided that all copyright and other proprietary notices contained on the materials are retained. The use of software, including scripts, agents, or robots, is generally prohibited and may result in the loss of access to these resources for the entire European University Institute community
Isbn
9783319453187
Level of compression
uncompressed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1007/978-3-319-45318-7
Other physical details
20 illustrations in color.
Quality assurance targets
absent
Reformatting quality
access
Specific material designation
remote
System control number
(OCoLC)962750882

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