Coverart for item
The Resource Histamine H4 receptor : a Novel Drug Target For Immunoregulation and Inflammation, Holger Stark, (electronic resource)

Histamine H4 receptor : a Novel Drug Target For Immunoregulation and Inflammation, Holger Stark, (electronic resource)

Label
Histamine H4 receptor : a Novel Drug Target For Immunoregulation and Inflammation
Title
Histamine H4 receptor
Title remainder
a Novel Drug Target For Immunoregulation and Inflammation
Statement of responsibility
Holger Stark
Creator
Subject
Language
  • eng
  • eng
Summary
H4 R is the newest member of the histamine receptor family, which was discovered about twelve years ago. It is considered a very promising drug target. The effort to improve the pharmacokinetic properties of the currently available H4 R ligands is reflected in a steadily growing number of scientific publications and patent applications. Preclinical data strongly confirms the need for novel potent H4 R ligands to explore their therapeutic value in allergy, inflammation, autoimmune disorders, and possibly, cancer. Readers will be provided with extensive knowledge on histamine metabolism, as well as cellular histamine transport, storage and release, effects of histamine and histamine receptor ligands, with particular attention to the H4 R, on inflammatory cells including mast cells, basophils, eosinophils, neutrophils, macrophages, dendritic cells, and T cells. The present knowledge on the regulatory role of histamine and the therapeutic exploitation of histamine receptor ligands in atopic diseases, with emphasis on human and animal models of asthma, allergic dermatitis and pruritus are discussed.--
Assigning source
Provided by publisher
Cataloging source
DE-B1597
http://library.link/vocab/creatorName
Stark, Holger,
Government publication
other
Language note
In English
Nature of contents
dictionaries
Series statement
Open Access e-Books
http://library.link/vocab/subjectName
  • Histamine
  • Life sciences
Target audience
specialized
Label
Histamine H4 receptor : a Novel Drug Target For Immunoregulation and Inflammation, Holger Stark, (electronic resource)
Link
https://doi.org/10.2478/9788376560564
Instantiates
Publication
Copyright
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Chapter 6 Histamine in Atopic Disorders: Atopic Dermatitis and Pruritus
  • Chapter 7 Non-professional Histamine Producing Cells, Immune Responses and Autoimmunity
  • Chapter 8 Histamine in Cancer
  • Chapter 9 Non Receptor-mediated Histamine Actions
  • Chapter 10 Perspectives in H4R Research and Therapeutic Exploitation
  • List of Figures
  • List of Tables
  • Index
  • Frontmatter
  • Contents
  • Preface
  • Chapter 1 The histamine H4 receptor story
  • Chapter 2 Histamine H4 Receptor Ligands
  • Chapter 3 Histamine Metabolism
  • Chapter 4 Histamine Receptors and Inflammatory Cells
  • Chapter 5 Histamine in Asthmatic and Fibrotic Lung Disorders
Control code
9788376560564
Extent
1 online resource
Form of item
online
Isbn
9788376560564
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.2478/9788376560564
Specific material designation
remote
System control number
(OCoLC)1110441526
Label
Histamine H4 receptor : a Novel Drug Target For Immunoregulation and Inflammation, Holger Stark, (electronic resource)
Link
https://doi.org/10.2478/9788376560564
Publication
Copyright
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • Chapter 6 Histamine in Atopic Disorders: Atopic Dermatitis and Pruritus
  • Chapter 7 Non-professional Histamine Producing Cells, Immune Responses and Autoimmunity
  • Chapter 8 Histamine in Cancer
  • Chapter 9 Non Receptor-mediated Histamine Actions
  • Chapter 10 Perspectives in H4R Research and Therapeutic Exploitation
  • List of Figures
  • List of Tables
  • Index
  • Frontmatter
  • Contents
  • Preface
  • Chapter 1 The histamine H4 receptor story
  • Chapter 2 Histamine H4 Receptor Ligands
  • Chapter 3 Histamine Metabolism
  • Chapter 4 Histamine Receptors and Inflammatory Cells
  • Chapter 5 Histamine in Asthmatic and Fibrotic Lung Disorders
Control code
9788376560564
Extent
1 online resource
Form of item
online
Isbn
9788376560564
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.2478/9788376560564
Specific material designation
remote
System control number
(OCoLC)1110441526

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